ea0081p354 | Diabetes, Obesity, Metabolism and Nutrition | ECE2022
Lengton Robin
, Iyer Anand
, Valk Eline van der
, Voorn Bibian van der
, van Rossum Elisabeth
Background: Mounting evidence points to an association between increased glucocorticoid (GC) action and weight gain. However, the response to GCs is not only determined by GC serum concentrations, but also by individual differences in tissue-specific sensitivity, influenced by genetic and acquired (e.g. disease-related) factors. The extent to which differences in GC sensitivity may influence development of (abdominal) obesity, or vice versa, is poorly understood. In this study...